Publications

AOC 1044 induces exon 44 skipping and restores dystrophin protein in preclinical models of Duchenne muscular dystrophy

Usue Etxaniz, Isaac Marks, Tyler Albin, Matthew Diaz, Raghav Bhardwaj, Aaron Anderson, Olecya Tyaglo, Tiffany Hoang, Maria Azzurra Missinato, Kristoffer Svensson, Ben Badillo, Philip R Kovach, Laura Leung, Michael Cochran, Hae Won Kwon, Md Nur Ahad Shah, Rika Maruyama, Toshifumi Yokota, Venkata R Doppalapudi, Beatrice Darimont, Husam S Younis, W Michael Flanagan, Arthur A Levin, Hanhua Huang, Georgios Karamanlidis
Nucleic Acids Research, Volume 53, Issue 6, 11 April 2025, gkaf241, https://doi.org/10.1093/nar/gkaf241

Publications

Structure–Activity Relationship of Antibody–Oligonucleotide Conjugates: Evaluating Bioconjugation Strategies for Antibody–Phosphorodiamidate Morpholino Oligomer Conjugates for Drug Development

Journal of Medicinal Chemistry
Michael Cochran, Isaac Marks, Tyler Albin, Danny Arias, Philip Kovach, Beatrice Darimont, Hanhua Huang, Usue Etxaniz, Hae Won Kwon, Yunyu Shi, Matthew Diaz, Olecya Tyaglo, Arthur Levin, and Venkata Ramana Doppalapudi. Journal of Medicinal Chemistry 2024 67 (17), 14868-14884. DOI: 10.1021/acs.jmedchem.4c00803

Publications

Structure–Activity Relationship of Antibody–Oligonucleotide Conjugates: Evaluating Bioconjugation Strategies for Antibody–siRNA Conjugates for Drug Development

Journal of Medicinal Chemistry
Michael Cochran, Danny Arias, Rob Burke, David Chu, Gulin Erdogan, Michael Hood, Philip Kovach, Hae Won Kwon, Yanling Chen, Michael Moon, Christopher D. Miller, Hanhua Huang, Arthur Levin, and Venkata Ramana Doppalapudi. Journal of Medicinal Chemistry 2024 67 (17), 14852-14867. DOI: 10.1021/acs.jmedchem.4c00802